ENGINEERING B CELL⁠-⁠BASED PROTEIN FACTORIES TO TREAT SERIOUS DISEASES

Walking Fish is rapidly advancing cell-based therapeutics to treat serious diseases, concentrating on oncology and regenerative therapies.

 
 
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ABOUT US

HARNESSING THE POWER OF LOCALLY ACTING PROTEINS USING B CELL FACTORIES 

Walking Fish has created a broad B cell platform for oncology, regenerative medicine, autoimmune disease, and recombinant antibody production. As a leader in B cell engineering, Walking Fish has made critical advances in engineering technologies and has a deep understanding of B cell biology.

 
 

What’s in a name 

Walking Fish draws its inspiration from the remarkable regenerative capacity of the Axolotl, colloquially known as a Walking Fish. Learn more about our company culture and join our amazing team.

 
 
 
 
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OUR TEAM

Co-founded and led by Lewis “Rusty” Williams – a repeat entrepreneur and CEO with a successful track record of founding and growing biotech companies – Walking Fish has assembled a distinguished team of cell engineering, manufacturing, and clinical experts supported by world-renowned scientific and strategic advisors.

OUR SCIENCE

B Cell

THE ROLE OF B CELLS

Walking Fish’s engineered B cells serve as protein factories, delivering multiple potent therapeutic proteins.

B cells and their progeny are known to be good producers of antibodies. Walking Fish utilizes the protein production capabilities of B cells by engineering B cells to produce proteins as therapeutics. Walking Fish B cells are directed to specific tissues or homed to their “native” tissues.

There are many potential therapeutic applications using B cells. WFT is at the forefront of this burgeoning field. Walking Fish B cells have the potential to produce engineered antibodies for infectious diseases, replacement proteins for deficiency diseases, immune-inhibitory proteins in autoimmune diseases, and regenerative proteins. B cells are also excellent at antigen-presentation and Walking Fish’s engineered B cells have immense potential in treating cancer by enhancing the antitumor immune response.

WFT B Cell Modalities

B Cell Modalities

Payloads are directed towards:

  • Oncology: Immune stimulation

  • Rare Deficiency Disease: Replacement Proteins

  • Regenerative Medicine: Regenerative Proteins

  • Autoimmune Disease: Immune-inhibitory proteins

  • Infectious Disease: Engineered antibodies

PIPELINE